Hemodynamics
Coronary Perfusion Pressure Calculator
Diastolic pressure minus wedge pressure, the pressure that fills the coronary arteries, which perfuse mainly in diastole.
Formula
DBP - PAOP
Reference: Normal 60–80
How it is used
- Normal coronary perfusion pressure (DBP − PAOP) is 60–80 mm Hg.
- The left ventricle fills its coronary arteries mainly in diastole, so a low diastolic pressure, a high wedge or a short diastole (tachycardia) all cut coronary flow.
- An intra-aortic balloon pump raises diastolic pressure to improve coronary perfusion (see IABP Management).
- During CPR coronary perfusion pressure is measured differently (aortic minus right atrial diastolic pressure); no patient reached ROSC below 15 mm Hg (Paradis 1990).
Related one-pagers
- Shock Types at a GlanceCardiogenic shock is hypoperfusion from pump failure: classically SBP <90 for ≥30 min or pressors needed, CI <2.2 L/min/m² and PCWP >15. A rising LVEDP backs up into the lungs and lowers coronary perfusion pressure (aortic diastolic minus LVEDP), worsening ischemia. In current US registries (Critical Care Cardiology Trials Network) heart-failure shock outnumbers AMI shock.
- IABP ManagementInflate · Mid T wave; dicrotic notch · Raises diastolic pressure and coronary perfusion
- ACLS Algorithms in BriefCompressions move blood two ways: they squeeze the heart between sternum and spine (the cardiac pump) and raise intrathoracic pressure so blood leaves the chest (the thoracic pump). Done well, they deliver roughly a quarter to a third of normal cardiac output. The myocardium is perfused almost entirely during the release phase, driven by coronary perfusion pressure (CPP): aortic diastolic pressure minus right atrial diastolic pressure.
- CapnographyDuring CPR, cardiac output is roughly a quarter to a third of normal and EtCO₂ follows it closely at a fixed ventilation rate. Overventilation lowers EtCO₂ and a slow rate raises it, so the number only reflects compressions when ventilation is steady at 1 breath every 6 seconds (AHA 2025). Sodium bicarbonate releases CO₂ (50 mEq can generate up to about 1 L), giving a transient rise that is not ROSC. Epinephrine can lower EtCO₂ for a few minutes despite raising coronary perfusion pressure.
Related calculators
- Cardiac Index (CI)
- Cardiac Output (Fick Principle)
- Cardiac Output (HR × SV)
- Cerebral Perfusion Pressure (CPP)
- Ejection Fraction (EF)
- Mean Arterial Pressure (MAP)
- Oxygen Delivery (DO₂)
- Pulmonary Vascular Resistance (PVR)
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For education and exam preparation only. Follow your institution’s protocols. For education and exam preparation only. Verify results independently and follow your institution’s protocols. Not a substitute for clinical judgment.