Anticoagulation, endocrine and GI
Naloxone (Narcan) drip
Narcan
Dosing
| Start | Two-thirds of the bolus dose that restored breathing, per hour |
|---|---|
| Titrate | To breathing, not to full alertness |
| Maximum | By response |
| Common bags | 4 mg in 100 mL (40 mcg/mL); 2 mg in 500 mL (4 mcg/mL) |
| Dose units | mg/h |
Line and administration
- Peripheral or central
Watch for
- Withdrawal, agitation and vomiting with too much
- Long-acting opioids outlast boluses: watch after stopping the infusion
Naloxone: full drug monographIndications, mechanism, pharmacokinetics, cautions and every dose the app lists.
In the one-pagers
- Toxidromes and AntidotesReversal antidotes: Opioids: Naloxone 0.2–2 mg IV/IM/IO or 2–4 mg nasal, every 2–3 min: Goal is breathing; may wear off first
- ACLS Algorithms in BriefReversible causes: bedside clues and ultrasound: Toxins: History, pupils, wide QRS, long QT: Naloxone, lipid, bicarbonate or calcium as fits
- BLS, High-Quality CPR and ChokingSpecial situations: Suspected opioid overdose: CPR first if no pulse; naloxone if available, without interrupting compressions
- ED Triage and ESIDecision point A: lifesaving intervention now: Medications: Naloxone, dextrose, epinephrine, atropine, adenosine, dopamine: Aspirin, IV nitroglycerin, antibiotics, heparin, analgesics
- CapnographySedation, opioids, nasal capnography and transport: Apnea: no waveform, no effort. Stimulate, ventilate, consider naloxone or reversal.
- Mental Health: Meds and CommunicationOpioid use disorder in the hospital: Tolerance falls fast after detox or a lapsed naltrexone dose, so overdose risk is high after discharge; send patients home with naloxone (AHA 2025 advises it after any opioid overdose).
Practice Toxidromes and Antidotes questions free85 exam-style questions with rationales on the topic where naloxone comes up most. No account or download needed.
Other anticoagulation, endocrine and gi
- Heparin
- Insulin (regular)
- Amiodarone
- Diltiazem
- Octreotide
- Pantoprazole
- Furosemide
- Argatroban
- Bivalirudin
- Procainamide
- Lidocaine
- Magnesium sulfate
- Eptifibatide
- Bumetanide
Practice free in your browser3,800+ exam-style questions with rationales. No account, no ads. Also free on the App Store and Google Play.
For education and exam preparation only. Follow your institution’s protocols. Study aid: check every dose against the order, the bag label, your pump library and your institution's protocol.